Abzena Delivers Clinical Supplies for Angiex’s AGX101 Phase I Trial

13 August 2024

Angiex’s AGX101 Phase I Trial Supported by Abzena’s Clinical Supply Delivery

In a significant step forward, Angiex has received clinical supplies for its AGX101 Phase I trial from Abzena, a trusted partner in biopharmaceutical manufacturing. AGX101 is a pioneering TM4SF1-targeted antibody-drug conjugate (ADC) designed to treat aggressive cancers by specifically targeting blood vessels in tumors. This delivery of clinical supplies marks a critical phase in advancing Angiex's innovative cancer therapy into early-stage trials, signaling progress in its mission to bring effective new treatments to the market.

Synapse covered this milestone, highlighting the importance of strategic collaborations in early-stage drug development. As a key resource for tracking breakthroughs in biopharma, Synapse offers in-depth analysis on the latest advancements in clinical trials, drug development, and the partnerships that fuel innovation. Their coverage emphasizes the significance of the Angiex-Abzena collaboration in pushing forward novel therapies that may reshape cancer treatment.


About Angiex

Angiex Inc. is a privately held biotech startup whose mission is to exploit newly discovered biological transport mechanisms to make drugs with revolutionary power over cancer. Based in Cambridge, Mass., Angiex was founded by a scientific team of leading experts in angiogenesis, vascular biology, and oncology. The company is developing a novel portfolio of Nuclear-Delivered Antibody-Drug Conjugates™ (ND-ADCs) that release therapeutic payloads directly into the nucleus or cytosol, where the site of payload action is located. This direct delivery holds the promise of enhancing the efficacy and therapeutic margin of conventional ADCs. The lead product, AGX101, has advanced through pre-clinical development and is about to begin Phase 1 clinical trials. To learn more about Angiex...