Abzena Supplies Clinical Trial Material for Angiex’s Phase I Study of AGX101, a First-in-Class TM4SF1-directed ADC

09 August 2024

Angiex’s AGX101 Phase I Study Receives Critical Support from Abzena

Angiex has made significant strides in its Phase I study of AGX101, a first-in-class TM4SF1-directed antibody-drug conjugate (ADC) designed to treat aggressive cancers by targeting tumor blood vessels. Abzena, a leading biopharmaceutical services provider, plays an essential role in supporting the trial by supplying the critical clinical trial materials necessary to advance this innovative therapy.

Clinical Research News recently covered the collaboration, highlighting how Abzena’s expertise in cGMP manufacturing has enabled Angiex to progress AGX101 through clinical development. As a leading outlet for news on clinical trials and research innovation, Clinical Research News emphasizes the importance of partnerships like that between Angiex and Abzena in accelerating the development of novel cancer treatments. Their coverage underscores the growing promise of ADC therapies in addressing unmet needs in oncology.


About Angiex

Angiex Inc. is a privately held biotech startup whose mission is to exploit newly discovered biological transport mechanisms to make drugs with revolutionary power over cancer. Based in Cambridge, Mass., Angiex was founded by a scientific team of leading experts in angiogenesis, vascular biology, and oncology. The company is developing a novel portfolio of Nuclear-Delivered Antibody-Drug Conjugates™ (ND-ADCs) that release therapeutic payloads directly into the nucleus or cytosol, where the site of payload action is located. This direct delivery holds the promise of enhancing the efficacy and therapeutic margin of conventional ADCs. The lead product, AGX101, has advanced through pre-clinical development and is about to begin Phase 1 clinical trials. To learn more about Angiex...