Angiex Initiates Phase 1 Clinical Trial of AGX101

09 August 2024

Angiex Begins Phase 1 Clinical Trial for TM4SF1-Targeted ADC AGX101

Angiex has commenced its Phase 1 clinical trial for AGX101, a pioneering antibody-drug conjugate (ADC) that specifically targets tumor vasculature. AGX101 is designed to disrupt the blood vessels that nourish tumors, representing a novel strategy in oncology. This innovative therapy holds great potential for addressing hard-to-treat cancers and marks an important step in Angiex’s efforts to deliver targeted treatments for patients.

Contract Pharma covered this exciting development, drawing attention to Angiex’s advancement in cancer therapeutics. As a go-to source for pharmaceutical manufacturing and development news, Contract Pharma provides valuable insight into the significance of early clinical trials like this one. Their article spotlights AGX101 as a promising player in the ADC space, underscoring the growing importance of precision oncology in cancer treatment.


About Angiex

Angiex Inc. is a privately held biotech startup whose mission is to exploit newly discovered biological transport mechanisms to make drugs with revolutionary power over cancer. Based in Cambridge, Mass., Angiex was founded by a scientific team of leading experts in angiogenesis, vascular biology, and oncology. The company is developing a novel portfolio of Nuclear-Delivered Antibody-Drug Conjugates™ (ND-ADCs) that release therapeutic payloads directly into the nucleus or cytosol, where the site of payload action is located. This direct delivery holds the promise of enhancing the efficacy and therapeutic margin of conventional ADCs. The lead product, AGX101, has advanced through pre-clinical development and is about to begin Phase 1 clinical trials. To learn more about Angiex...