First Patient Dosed with ADC Therapy Designed to Disrupt Tumor Blood Supply

13 August 2024

Angiex Reaches Major Milestone in Cancer Therapy Development with First Patient Dosed in Phase 1 ADC Trial

Angiex has dosed the first patient in its Phase 1 clinical trial for its novel antibody-drug conjugate (ADC) therapy, a significant achievement in the development of treatments targeting blood vessels in tumors. This innovative therapy represents a breakthrough approach in oncology, leveraging the potential of ADCs to deliver targeted cancer treatments with greater precision. The dosing milestone brings Angiex one step closer to offering new hope for patients with difficult-to-treat cancers.

BioPharma Reporter provided extensive coverage of this milestone, underscoring its relevance in the biopharmaceutical industry. As a trusted source for updates on biopharma innovation and clinical development, BioPharma Reporter reaches a broad audience of industry professionals and thought leaders. Their report on Angiex’s clinical trial initiation highlights the therapeutic potential of Angiex’s ADC and its possible impact on the future of cancer treatments.


About Angiex

Angiex Inc. is a privately held biotech startup whose mission is to exploit newly discovered biological transport mechanisms to make drugs with revolutionary power over cancer. Based in Cambridge, Mass., Angiex was founded by a scientific team of leading experts in angiogenesis, vascular biology, and oncology. The company is developing a novel portfolio of Nuclear-Delivered Antibody-Drug Conjugates™ (ND-ADCs) that release therapeutic payloads directly into the nucleus or cytosol, where the site of payload action is located. This direct delivery holds the promise of enhancing the efficacy and therapeutic margin of conventional ADCs. The lead product, AGX101, has advanced through pre-clinical development and is about to begin Phase 1 clinical trials. To learn more about Angiex...